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pentobarbital will lower the level or effect of parecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep an eye on.pentobarbital will lessen the level or result of loratadine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will reduce the level or effect of cobimetinib by influencing h